Research Interests

Publications

An audit of outcome including patient satisfaction with immediate breast reconstruction performed by breast surgeons.
M Berry, AD Jenkinson, R Carpenter.
Ann R Col Surg Eng. 1998; 30: 173-7.

Vector Manometry and Lower Oesophageal Sphincter Dynamics.
AD Jenkinson, SM Scott, SS Kadirkamanathan.
Gut 2000; 46: 740.

Prospective study of symptoms and gastro-oesophageal reflux 10 years after posterior partial fundoplication (letter).
AD Jenkinson, SM Scott, SS Kadirkamanathan.
Br J Surg 2000; 87: 122.

Is distribution of vacancies for hospital jobs a reflection of the new NHS?
AD Jenkinson, CI Clark.
BMJ 2000; 321: 453.

Does intraductal breast cancer spread in a segmental distribution? An analysis of tumour burden following segmental mastectomy using tumour bed biopsies.
AD Jenkinson, RA Al-Mufti, Y Mohsen, MJ Berry, C Wells, R Carpenter.
European Journal of Surgical Oncology 2001; 27: 21-5.

Compliance measurement of the lower oesophageal sphincter in achalasia and gastro-oesophageal reflux disease.
AD Jenkinson, SM Scott, SS Kadirkamanathan, DF Evans.
Dig Dis Sci 2001; 46 (9):1937-1942.

Comparison of ankle-brachial pressure index measurements using an automated oscillometric device with the standard doppler ultrasound technique.
A Ramanathan, PJ Conaghan, AD Jenkinson, CR Bishop.
ANZ J Surg 2003; 73 (3): 105-8

Comparison of medical and surgical treatment for gastro-oesophageal reflux disease: the relationship between symptom response and oesophageal acid exposure.
AD Jenkinson , SS Kadirkamanathan, SM Scott, E Yazaki, DF Evans.
BJS Nov 2004

Laparoscopic feeding jejunostomy in esophagogastric cancer.
Jenkinson AD, Lim J, Agrawal N, Menzies D.
Surg Endosc. 2007 Feb;21(2):299-302

Presentations / Abstracts presented

British Society of Gastroenterology: Edinburgh 22-25 March 1999
Electronic impedence tomography (EIT) as an aid to diagnosis of gastric dysmotility.
E Yazaki, AD Jenkinson, J Powel-Tuck, DF Evans.

American Gastroenterology Association - Digestive Disease Week: Orlando 16-20 May 1999
Do patients with oesophageal dysmotility have a higher risk of dysphagia following 3600 fundopliction for gastro-oesophageal reflux?
AD Jenkinson, SS Kadirkamanathan, SM Scott, DF Evans, J Rogers
Gastroenterology 1999; 116: A198.

How does oesophageal compliance change in achalasia?
AD Jenkinson, E Yazaki, SM Scott, S Walker, DF Evans
Gastroenterology 1999; 116: A198.

American Gastroenterology Association - Digestive Disease Week: San Diego May 21-24 2000
Patients with gastroesophageal reflux disease have highly compliant lower oesophageal sphincters
AD Jenkinson, E Yazaki, SM Scott, S Walker, DF Evans
Gastroenterology 2000; 118: 2613.

Vector manometry of the lower oesophageal sphincter - how reproducible is it?
AD Jenkinson, E Yazaki, SM Scott, DF Evans.
Gastroenterology 2000; 118: 5419.

Association of Upper GI Surgeons - Manchester: September 26-27 2002
Control of acid reflux following laparoscopic fundoplication: Preoperative factors affecting outcome.
AD Jenkinson, SS Kadirkamanathan, SM Scott, DF Evans
Published in the BJS

American Gastroenterology Association - Digestive Disease Week: Orlando May 18-21 2003
Comparison of medical and surgical treatment for gastroesophageal reflux disease: Is symptom response a good indicator of success?
AD Jenkinson, E Yazaki, SM Scott, DF Evans, SS Kadirkamanathan
Published in Gastroenterology

Post-operative assessment is of no value in predicting gastroesophageal reflux disease following anti-reflux surgery.
AD Jenkinson, E Yazaki, SM Scott, DF Evans, SS Kadirkamanathan
Published in Gastroenterology

12th Annual Congress of the European Association of Endoscopic Surgeons - Barcolona June 9 2004
Laparoscopic Incisional Hernia Paper: A Self Centred Approach.
A Engledow, AD Jenkinson, M Scarf, S Warren, R Motson

12th Annual Congress of the European Association of Endoscopic Surgeons - Barcolona June 9 2004
Effectiveness of Laparoscopic Feeding Jejunostomy for Oesophago-gastric Carcinoma
AD Jenkinson J Lim N Ward D Menzies

Carribean Society of Surgerey - St Lucia June 2007
Beriberi following Laparoscopic Gastric Bypass
AD Jenkinson

European Association of Endoscopic Surgeons - Athens September 2007
Laparoscopic Gastric Bypass versus Laparsocpic Sleeve Gastrectomy: Prospective Comparative Study
Jenkinson AD, Ghanbari A, Mannur K

Video Presentation

12th Annual Congress of the European Association of Endoscopic Surgeons - Barcolona June 9 2004
Laparoscopic Excision of Oesophageal Inclusion Cyst
AD Jenkinson, D Menzies

Abstract of Master of Surgery Thesis

THE ROLE OF PHYSIOLOGICAL INVESTIGATION IN THE CLINICAL MANAGEMENT OF FOREGUT MOTILITY DISORDERS

Investigation of oesophageal physiology is increasingly being used to diagnose disorders of foregut motility, in particular gastro-oesophageal reflux disease (GORD) and achalasia. This work examines the clinical usefulness of several investigations. These include; those already in common use (oesophageal station manometry and 24 hour pH measurement), one that has been advocated as superior to current investigation but is not yet in routine use (vector manometry) and a newer investigation that may be of use in the future (compliance measurement).

The role of station pull-through manometry and 24 hour oesophageal pH monitoring in the prediction of postoperative outcome following laparoscopic antireflux surgery was investigated. In this study, using a population of 130 patients with GORD, two factors were found to be significant in the prediction of surgical outcome. Preoperatively patients with either severe reflux or an oesophageal motility disorder were found to have an increased risk of residual reflux following surgery. The identification of these risk factors will assist in the interpretation of preoperative oesophageal physiology investigations.

The clinical usefulness of vector manometry of the lower oesophageal sphincter (LOS) was assessed. The investigation was performed on 17 healthy volunteers and 59 patients before and after antireflux surgery. Surgery increased median VV from 734 mm.mmHg2 to 3452 mm.mmHg2. Twenty-eight (48%) patients were found to have LOS VV's below the normal range before surgery. There was no difference in surgical outcome between the groups with and without a mechanically defective LOS preoperatively. There was poor reproducibility in VV measurement between pull-throughs. Preoperative vector manometry was not useful in the prediction of surgical outcome. This could be due to a combination of the investigations poor reproducibility and the multifactorial nature of GORD.

Finally, compliance measurement of the LOS and oesophageal body was performed on 22 achalasics, 14 patients with GORD and 14 volunteers. In achalasia compliance of the oesophageal body was significantly higher than in controls, whereas LOS compliance was lower. Patients with GORD had a highly compliant LOS in comparison to controls. Further studies, using this novel technique, may contribute to our understanding of the pathophysiology of these conditions.

The Master of Surgery examination was passed in July 2001.